Pregnant with multiple sclerosis?

MS in pregnancy

There’s good news for women with multiple sclerosis (MS) who are pregnant or thinking about becoming pregnant. A new study shows that pregnant women with multiple sclerosis are only slightly more likely to have cesarean deliveries and babies with a poor prenatal growth rate than women who do not have MS. Plus, the women with MS were no more likely to have other pregnancy problems, such as pre-eclampsia and other high blood pressure problems and premature rupture of membranes, than women in the general population.

The large study included an estimated 18.8 million deliveries, with about 10,000 of those occurring in women with MS. The women with MS were more likely than women without chronic medical conditions (2.7% for women with MS compared to 1.9% for women without chronic medical conditions) to have a baby with intrauterine growth restriction, defined as a weight less than the tenth percentile for the gestational age, as measured by ultrasound. Women with MS were more likely to have a cesarean delivery than those in the general population (42% versus 33%).

“These results are reassuring for women with MS,” says study author Eliza Chakravarty, MD, MS, of Stanford University School of Medicine in Stanford, CA. “Women and their doctors have been uncertain about the effect of MS on pregnancy, and some women have chosen to delay or even avoid pregnancy due to the uncertainty. We found that women with MS did not have an increased risk of most pregnancy complications.”

The study also looked at women who had diabetes prior to becoming pregnant (not gestational diabetes), and found that they had higher rates of complications than women with MS and high rates of complications in areas where the women with MS did not have increased rates.

The study was published in the November 18, 2009, online issue of Neurology.

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